产品货号：
Z21581
中文名称：
NOL3抗体
英文名称：
Anti-NOL3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NOL3 Antibody |
| 指标别名 | Apoptosis repressor with CARD;ARC;CARD2;MYP;NOL3;NOP;NOP30;Nucleolar protein 3;Nucleolar protein of 30kDa |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | NOL3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human Apoptosis repressor with CARD(91-106aa WDWQHVGPGYRDRSYD),identical to the related rat sequence,and different from the related mouse sequence by one amino acid. |
| 实际分子量 | 30KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | NOL3(Nucleolar protein 3),also known as ARC,NOP30,CARD2 and MYP,is a protein that in humans is encoded by the NOL3 gene.NOL3 has been shown to interact with SFRS9 and Caspase 8.By genomic sequence analysis,Stoss et al.(1999) determined that the NOL3 gene,which encodes NOP30 and MYP and which they called NOP,is composed of 4 exons.The alternative 5-prime splice site that generates the 2 isoforms is located in exon 2.It is reported that expression of the ARC cDNA encoding the smaller transcript inhibited apoptosis in a dose-dependent manner when coexpressed with CASP8 but not when coexpressed with CASP9.ARC also inhibited apoptosis induced by stimulation of CD95/FAS,tumor necrosis factor receptor-1,and TRAMP/death receptor-3.Enzymatic analysis showed that ARC inhibits the enzymatic activity of CASP8.Immunoprecipitation and immunoblot analysis indicated that ARC interacts with CASP2 and CASP8 through its N-terminal death effector domain but does not interact with CASP1,CASP3,or CASP9. |
| Uniprot ID | O60936 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | nucleolar protein 3(apoptosis repressor with CARD doma) |
| 蛋白名全称 | Nucleolar protein 3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：NOL3抗体，NOL3多抗，Anti-NOL3 Antibody